Chemistry

The Department of Chemistry offers courses in general chemistry, organic chemistry, physical and analytical chemistry, biochemistry, biophysical chemistry, inorganic chemistry, and thermodynamics. The department also offers chemistry labs.

For questions about specific courses, contact the department:

Undergraduate Departmental Office: 340 Havemeyer
212-854-2163

Graduate Departmental Office: 344 Havemeyer
212-854-2433

Chemistry Main Office: 344 Havemeyer
212-854-2202
Office Hours: Monday–Friday, 9:00 a.m.–5:00 p.m.

Web: www.columbia.edu/cu/chemistry


Directory of Classes

The course information displayed on this page relies on an external system and may be incomplete. Please visit Chemistry on the Directory of Classes for complete course information for:
Fall 2016
Spring 2017

After finding your course in the Directory of Classes, click on the section number to open an expanded view. The "Open To" field will indicate whether the course is open to School of Professional Studies students. If School of Professional Studies is not included in the field, students may still be able to cross-register for the course by obtaining permission after being admitted to an academic program.


CHEM BC2001 General Chemistry I. 5 points.

BC: Fulfillment of General Education Requirement: Quantitative and Deductive Reasoning (QUA).
All students enrolled in BC2001x must also be enrolled in one section of BC2011 that is on the SAME DAY as BC2012 .

Prerequisites: Algebra (Math SAT I score of 600 or permission of the instructor for first-year students).
Corequisites: CHEM BC2011 and CHEM BC2012 \nLecture: MWF 11:00-11:50; Lab lecture and laboratory one afternoon: MTWRF: 1:10-5:00. Counts towards Lab Science requirement.

Atoms; elements and compounds; gases; solutions; equilibrium; acid-base, precipitation, and oxidation-reduction reactions; thermochemistry. Laboratory experience with both qualitative and quantitative techniques.

Fall 2017: CHEM BC2001
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 2001 001/06144 M W F 11:00am - 11:50am
Room TBA
Rachel Austin 5 72/192

CHEM BC2002 General Chemistry II. 5 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM BC2001 or permission of the instructor. Students who have completed CHEM BC3230 or its equivalent may not subsequently receive credit toward the degree for CHEM BC2002. Lecture: TuTh 8:40-9:55; Lab lecture and laboratory: M 1:10-5:00.
Corequisites: Counts towards Lab Science requirement.

Kinetics and mechanisms of chemical reactions; nuclear chemistry and radioactivity; atomic and molecular structure; selected topics in environmental chemistry, organic chemistry, and biochemistry.

CHEM BC2102 General Chemistry II Laboratory. 2 points.

Not offered during 2017-18 academic year.

Prerequisites: General Chemistry I with laboratory.
Corequisites: General Chemistry II lectures or equivalent and permission of instructor. Lab lecture and laboratory: M 1:10-5:00.

Laboratory portion of CHEM BC2002.

CHEM BC3230 Organic Chemistry I. 3 points.

Prerequisites: CHEM BC2001 or equivalent. Credit will not be given for any course below the 3000 level after completing CHEM BC3230 or its equivalent. Lecture: MWF: 11:00-11:50.
Corequisites: With lab, counts towards Lab Science requirement.

Atomic and molecular structure; stereochemistry of organic molecules; introduction to organic reactions, reaction mechanisms, and synthesis.

Spring 2017: CHEM BC3230
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3230 001/07359 M W F 11:00am - 11:50am
202 Altschul Hall
Christian Rojas 3 179

CHEM BC3231 Organic Chemistry II. 3 points.

Prerequisites: CHEM BC3230. Lecture: MWF 10:00-10:50.

Extension of concepts from Organic Chemistry I to conjugated systems; chemistry of the carbonyl group; NMR and IR spectroscopy; bioorganic chemistry.

Fall 2017: CHEM BC3231
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3231 001/07716 M W F 10:00am - 10:50am
Room TBA
Christian Rojas 3 125

CHEM BC3232 Chemistry IV. 3 points.

Prerequisites: Organic Chemistry I. Optional parallel laboratory work: CHEM BC3338. CHEM C1404 is not an acceptable equivalent for CHEM BC3232; students who have taken even a single semester of organic chemistry will not receive subsequent credit for C1404. Lecture: MWF 10:00-10:50.

Selected aspects of general chemistry, primarily for pre-health professions and biological science students who have taken Organic Chemistry. Thermodynamics, equilibrium, kinetics, complex ions and coordination compounds, and radiochemistry, with applications to analytical chemistry and biochemistry.

Spring 2017: CHEM BC3232
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3232 001/07571 T Th 8:40am - 9:55am
Ll103 Diana Center
Benjamin Bostick 3 56

CHEM BC3242 Quantitative Analysis. 3 points.

This course is not a suitable substitute for CHEM BC3232 for students completing the pre-health requirements.

Prerequisites: CHEM BC3231, MATH V1101, and permission of instructor.
Corequisites: CHEM BC3338

Survey of topics appropriate for a student majoring in chemistry or biochemistry, including examinations of uncertainty analysis and data processing, use of basic laboratory equipment, complex equilibria (pH, solubility, etc.), advanced solution chemistry and chemical activity, and the theoretical foundations of modern techniques in electrochemistry, chromatography and analytical experimental techniques.

Spring 2017: CHEM BC3242
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3242 001/09229 M W F 11:00am - 11:50am
805 Altschul Hall
Jacob Alexander 3 21

CHEM BC3252 Thermodynamics and Kinetics. 3 points.

Prerequisites: CHEM BC3231, PHYS BC2001, PHYS BC 2002, MATH V1102 or MATH V1201. Lecture: MWF 10:00-10:50.

Introduction to the laws of thermodynamics; application primarily to ideal systems. Free energy and equilibrium. Kinetics: rate laws and mechanisms, experimental techniques.

Spring 2017: CHEM BC3252
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3252 001/07590 M W F 10:00am - 10:50am
805 Altschul Hall
Andrew Crowther 3 10

CHEM BC3253 Quantum Chemistry. 3 points.

Prerequisites: Physics and Calculus II or III or permission of instructor. Lecture: MWF 11:00-11:50.

Exact and approximate solutions to the Schrodinger equation. The structure of atoms and molecules. Chemical bonding and spectroscopy. Computer-based molecular modeling.

Fall 2017: CHEM BC3253
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3253 001/01266 M W F 11:00am - 11:50am
Room TBA
Andrew Crowther 3 13

CHEM BC3254 Methods and Applications in Physical Chemistry. 3 points.

Prerequisites: One semester of physical chemistry (CHEM BC3252, CHEM BC3253, or the equivalent). Lecture: MWF 10:00-10:50.

Advanced topics in physical chemistry, including statistical mechanics, reaction dynamics, surface science, spectroscopy, microscopy, and nanotechnology.  Particular emphasis will be placed on current applications in related fields such as biomedicine, engineering, and environmental science.

CHEM BC3271 Inorganic Chemistry. 3 points.

Prerequisites: CHEM BC3231x or Permission of Instructor. Lecture: TuTh 8:40-9:55.

Structure, bonding and spectroscopy in inorganic compounds: applications of group theory to chemistry; ligand field theory; vibrational and electronic spectroscopy of transition metal complexes; selected topics from coordination chemistry, organometallics, bioinorganic chemistry, solid state and materials chemistry, mineralogy, and biogeochemistry.

Spring 2017: CHEM BC3271
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3271 001/00435 T Th 8:40am - 9:55am
805 Altschul Hall
Michael Campbell 3 16

CHEM BC3272 Advanced Inorganic Chemistry. 3 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM BC3271 Inorganic Chemistry

This course combines builds on the foundation developed in Inorganic Chemistry (CHEM BC3271) and applies inorganic chemical concepts and techniques to specific applications. A particular focus will be on understanding the roles of the transition metals in biological systems.

CHEM BC3280 Advanced Organic Chemistry. 3 points.

Prerequisites: One year of organic chemistry. Lecture: MWF 9-9:50 AM.

Survey of topics in structural, mechanistic, and synthetic organic chemistry, including molecular orbital treatment of structure, bonding, and chemical reactivity; elucidation of organic reaction mechanisms; pericyclic reactions; stereoelectronic effects; reactive intermediates; asymmetric reactions; and natural product total synthesis.

CHEM BC3282 Biological Chemistry. 3 points.

Prerequisites: One year of Organic Chemistry, BIOL BC1502. Lecture: MWF 9:00-9:50.

Introduction to biochemical building blocks, macromolecules, and metabolism. Structures of amino acids, lipids, carbohydrates, nucleic acids. Protein structure and folding. Enzyme mechanisms, kinetics, allostery. Membranes and biosignaling. Catabolism and anabolism with emphasis on chemical intermediates, metabolic energy, catalysis by specific enzymes, regulation.

Fall 2017: CHEM BC3282
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3282 001/04565 M W F 9:00am - 9:50am
Room TBA
Christina Vizcarra 3 39

CHEM BC3283 Biological Chemistry II. 3 points.

Prerequisites: CHEM BC3282 or equivalent.

Advanced topics in the field of biochemistry, including enzyme mechanisms, pharmaceutical drug design, and disease therapies. Emphasis will be placed on discussion of current scientific literature.

Spring 2017: CHEM BC3283
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3283 001/05294 M W F 9:00am - 9:50am
530 Altschul Hall
Christina Vizcarra 3 12

CHEM BC3337 Modern Techniques of Organic Chemistry Laboratory. 2 points.

CHEM BC3333x + CHEM BC3337x = BC3335x

Prerequisites: CHEM BC3333x. Lecture: Tu 12:00-12:50; Laboratory one afternoon: Tu 1:10-5:30.

CHEM BC3338 Quantitative and Instrumental Techniques Laboratory. 3 points.

Prerequisites: CHEM BC3231, CHEM BC3333
Corequisites: For students not majoring in chemistry or biochemistry: CHEM BC3232 For students majoring in chemistry biochemistry, CHEM BC3242. Lab Lecture: Tu 1:10-2:00; Laboratory one afternoon: Tu, W, or Th.

Quantitative techniques in volumetric analysis, radiochemistry, spectrophotometry, and pH measurement. Data analysis with spreadsheets.

Spring 2017: CHEM BC3338
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3338 001/08694 T 2:10pm - 6:00pm
813 Altschul Hall
Jacob Alexander 3 7/0
CHEM 3338 002/04695 W 1:10pm - 5:00pm
813 Altschul Hall
Jacob Alexander 3 8/0
CHEM 3338 003/00442 Th 1:10pm - 5:00pm
813 Altschul Hall
Jacob Alexander 3 7/0

CHEM BC3340 Quantitative and Instrumental Techniques Laboratory. 5 points.

Not offered during 2017-18 academic year.

Prerequisites: General Chemistry with lab, Organic I lab.
Corequisites: For students not majoring in chemistry or biochemistry: CHEM BC3232 or CHEM BC3252. Lecture: Tu 1:10-2:00; Laboratory two afternoons: Tu 2:10-6:00 and Th 1:10-5:00.

Identical to CHEM BC3338, but with a greater variety and number of experiments.

CHEM BC3342 Quantitative and Instrumental Techniques Laboratory. 2 points.

CHEM BC3338 + CHEM BC3342 = BC3340

Prerequisites: CHEM BC3338. Laboratory one afternoon: Tu 2:10-6:00 or Th 1:10-5:00.

CHEM BC3348 Advanced Spectroscopy and Analysis Laboratory. 3 points.

Prerequisites: CHEM BC3333 and CHEM BC3253
Corequisites: CHEM BC3271

This course combines chemical synthesis, inorganic chemistry, physical chemistry, and nanoscience into experiments with an emphasis using spectroscopy to determine chemical structure and reactivity. You will gain experience with a range of instruments, techniques, calculations, and theories. Instrumentation will include UV-Visible, infrared, near-infrared, fluorescence, and Raman spectroscopy.

Spring 2017: CHEM BC3348
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3348 001/09131 W 1:10pm - 2:00pm
530 Altschul Hall
Andrew Crowther 3 12
CHEM 3348 001/09131 M W 1:10pm - 5:30pm
606 Altschul Hall
Andrew Crowther 3 12

CHEM BC3355 Biochemistry Laboratory Techniques. 5 points.

Prerequisites: Organic II lab (CHEM BC3333, BC3335, or equivalent); Quantitative analysis lab (BC3338, BC3340, or equivalent); Biochemistry (CHEM BC3282y, CHEM C3501, or equivalent). Lecture: M 1:10-12:50; Laboratory two afternoons: M 2:10-6:00 / W 1:10-5:00.

Theory and application of fundamental techniques for the isolation, synthesis and characterization of biological macromolecules including proteins, lipids, nucleotides and carbohydrates.  Techniques include spectroscopic analysis, gel electrophoresis, chromatography, enzyme kinetics, immunoblotting, PCR, molecular cloning and cell culture, as well as modern laboratory instrumentation, such as UV-Vis, GC-MS and HPLC.

Spring 2017: CHEM BC3355
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3355 001/06227 T 1:10pm - 2:00pm
530 Altschul Hall
Mary Sever 5 13
CHEM 3355 001/06227 Th 1:10pm - 5:00pm
606 Altschul Hall
Mary Sever 5 13
CHEM 3355 001/06227 T 2:10pm - 6:00pm
606 Altschul Hall
Mary Sever 5 13

CHEM BC3358 Advanced Chemical Synthesis Laboratory. 5 points.

Prerequisites: CHEM BC3333, CHEM BC3271, and CHEM BC3338
Corequisites: CHEM BC3253

Multistep and multi-day experiments in organic and inorganic synthesis via advanced synthetic methods. Experiments include solution phase, solid state, and photochemical syntheses. Products will be analyzed and characterized by a variety of methods, including: IR, NMR, and UV-Vis spectroscopy, and also by polarimetry, chiral GC, and GC/MS.

Fall 2017: CHEM BC3358
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3358 001/02507 T 1:10pm - 2:00pm
Room TBA
Marisa Buzzeo, Jean Vadakkan 5 10
CHEM 3358 001/02507 Th 1:10pm - 5:00pm
Room TBA
Marisa Buzzeo, Jean Vadakkan 5 10
CHEM 3358 001/02507 T 2:10pm - 6:00pm
Room TBA
Marisa Buzzeo, Jean Vadakkan 5 10

CHEM BC3365 Integrated Chemistry Laboratory. 3 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM BC3252 and CHEM BC3338 or equivalent.
Corequisites: Lecture: W 1:10-2:00; Laboratory: M 1:10-5:30 and W 2:10-6:30.

Experiments in kinetics, thermodynamics, and electrochemistry using instrumental methods; preparation and characterization of inorganic compounds; solids; some computer applications.

CHEM BC3368 Integrated Chemistry Laboratory II. 3 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM BC3253 and CHEM BC3338 or equivalent. Lecture: Tu 12:00-12:50; Laboratory: MW 1:10-5:00.

Experiments in spectroscopy and structure: UV-Vis, fluorescence, Raman, infrared spectra of organic and inorganic molecules and reactions.

CHEM BC3590 Senior Colloquium. 2 points.

Not offered during 2017-18 academic year.

Readings, discussions, and presentations about contemporary research in chemistry and biochemistry. Th 10:35-12:25.

CHEM BC3597 Problems in Chemistry. 2 points.

Prerequisites: CHEM BC3328 and permission of instructor. 4 hours of laboratory work by arrangement.

Individual research projects at Barnard or Columbia, culminating in a comprehensive written report.

Spring 2017: CHEM BC3597
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3597 001/06140  
Christian Rojas 2 0
CHEM 3597 002/01987  
Marisa Buzzeo 2 1
CHEM 3597 003/01343  
Dina Merrer 2 1
CHEM 3597 004/02372  
Michael Campbell 2 0
CHEM 3597 005/03664  
Andrew Crowther 2 1
CHEM 3597 006/04770  
Mary Sever 2 0
CHEM 3597 007/05169  
Rachel Austin 2 2
CHEM 3597 008/06203  
Christina Vizcarra 2 1
CHEM 3597 009/08335  
Benjamin Bostick 2 0
CHEM 3597 010/04887  
Dina Merrer 2 1
Fall 2017: CHEM BC3597
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3597 001/03664  
Christian Rojas, Dina Merrer 2 0
CHEM 3597 002/01537  
Marisa Buzzeo, Rachel Austin 2 0
CHEM 3597 003/05823  
Dina Merrer 2 0
CHEM 3597 004/07294  
Andrew Crowther, Rachel Austin 2 0
CHEM 3597 005/01343  
Rachel Austin, Michael Campbell 2 0
CHEM 3597 006/02865  
Mary Sever, Rachel Austin 2 0
CHEM 3597 007/08247  
Dina Merrer, Rachel Austin 2 0
CHEM 3597 008/02238  
Christina Vizcarra, Rachel Austin 2 0
CHEM 3597 009/01116  
Benjamin Bostick, Rachel Austin 2 0
CHEM 3597 010/06509  
Dina Merrer, Rachel Austin 2 1

CHEM BC3598 External Problems in Chemistry. 4 points.

Prerequisites: CHEM BC3328 and permission of instructor (a Barnard professor who will act as liaison) is required. Mandatory pass/fail grading. 8 hours of laboratory work by arrangement.

Individual research projects at institutions other than Barnard and Columbia, culminating in a comprehensive written report and oral presentation.

Spring 2017: CHEM BC3598
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3598 001/00188  
Dina Merrer 4 0

CHEM BC3599 Problems in Chemistry. 4 points.

Prerequisites: CHEM BC3328 and permission of instructor. 8 hours of laboratory work by arrangement.

Individual research projects at Barnard or Columbia, culminating in a comprehensive written report.

Spring 2017: CHEM BC3599
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3599 001/08950  
Christian Rojas 4 1
CHEM 3599 002/03432  
Marisa Buzzeo 4 1
CHEM 3599 003/06060  
Dina Merrer 4 1
CHEM 3599 004/08383  
Michael Campbell 4 1
CHEM 3599 005/02533  
Andrew Crowther 4 0
CHEM 3599 006/09449  
Mary Sever 4 2
CHEM 3599 007/05277  
Rachel Austin 4 3
CHEM 3599 008/09137  
Christina Vizcarra 4 1
CHEM 3599 009/07806  
Benjamin Bostick 4 0
CHEM 3599 010/06349  
Dina Merrer 4 0
Fall 2017: CHEM BC3599
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3599 001/02182  
Christian Rojas, Dina Merrer 4 1
CHEM 3599 002/05095  
Marisa Buzzeo, Rachel Austin 4 0
CHEM 3599 003/01197  
Dina Merrer 4 0
CHEM 3599 004/00639  
Andrew Crowther, Rachel Austin 4 1
CHEM 3599 005/03432  
Rachel Austin, Michael Campbell 4 0
CHEM 3599 006/03858  
Mary Sever, Rachel Austin 4 1
CHEM 3599 007/06747  
Dina Merrer, Rachel Austin 4 0
CHEM 3599 008/03187  
Christina Vizcarra, Rachel Austin 4 1
CHEM 3599 009/03848  
Benjamin Bostick, Rachel Austin 4 1
CHEM 3599 010/08439  
Dina Merrer, Rachel Austin 4 1

CHEM BC3901 Senior Honors Thesis. 4 points.

Enrollment restricted by invitation of the department.

Weekly seminar to accompany Senior Honors Thesis Lab (CHEM BC3903). Focus is on scientific presentation and writing skills and research conduct. 

Fall 2017: CHEM BC3901
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3901 001/00140 F 2:10pm - 4:00pm
Room TBA
Marisa Buzzeo, Rachel Austin 4 7
CHEM 3901 002/03671 F 2:10pm - 4:00pm
Room TBA
Rachel Austin, Michael Campbell 4 3

CHEM BC3902 Senior Honors Thesis. 4 points.

Enrollment restricted by invitation of the department.

Weekly seminar to accompany Senior Honors Thesis Lab (CHEM BC3903). Focus is on scientific presentation and writing skills and research conduct. 

Spring 2017: CHEM BC3902
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3902 001/09233 F 2:10pm - 4:00pm
805 Altschul Hall
Marisa Buzzeo 4 9
CHEM 3902 002/07009 F 2:10pm - 4:00pm
530 Altschul Hall
Christina Vizcarra 4 9

CHEM G4103 Organometallic Chemistry. 4.5 points.

Prerequisites: elementary organic chemistry. (Some background in inorganic and physical chemistry is helpful but not required.)

Main group and transition metal organometallic chemistry: bonding, structure, reactions, kinetics, and mechanisms.

CHEM G4137 Photonics & Spectroscopy. 4.5 points.

Discussion Section Required
Not offered during 2017-18 academic year.

Powerful photonics and spectroscopy tools are changing the way many physical and biological problems are addressed by revealing direct and precious energetic and dynamic information of molecular species inside live cells or novel materials. This full semester graduate course will not only provide fundamental knowledge of optics, laser, photonics, linear and nonlinear molecular spectroscopy, but also introduce physical principles of various emerging optical techniques including femotosecond spectroscopy, single-molecule spectroscopy, multi-photon nonlinear microscopy, label-free chemical imaging, super-resolution imaging, optical coherence tomography.

CHEM G4168 Materials Chemistry I. 4.5 points.

Prerequisites: sophomore Organic and Inorganic Chemistry.

This course will have two main themes. One theme will explore the design, synthesis, and properties of materials made from molecules. Topics that will be covered in this section of the course include the chemistry of liquid crystals, self-assembled monolayers, organic electronics, carbon-based nanostructures, self-assembled materials, and bio-inspired materials. A second theme will explore inorganic materials. It will compare the chemistry of chemical vapor deposition and vapor phase epitaxy to make solid state materials. It will further study the transformation from chemical bonds to solid-state band structure in materials and quantum size effects.

CHEM G4170 Biophysical Chemistry. 4.5 points.

Prerequisites: elementary physical and organic chemistry.

Recommended preparation: elementary biochemistry. Tactics and techniques for the study of large molecules of biological importance, analysis of the conformation of proteins and nucleic acids; hydrodynamic, scattering, and spectroscopic techniques for examining macromolecular structure.

CHEM G4172 Biorganic Topics. 4.5 points.

Not offered during 2017-18 academic year.

Prerequisites: elementary organic chemistry.

Recommended preparation: advanced organic chemistry. Various topics in bioactive molecules in the field centered on natural-products chemistry, metabolic transformations, and enzyme mechanisms. Biosysnthesis of natural products and some other bioorganic topics.

CHEM G4210 Writing Workshop for Chemists. 1 point.

Prerequisites: recommended for undergraduate students to have taken at least one semester of independent research.

This course offers undergraduate and graduate students an introduction to scientific writing and provides an opportunity for them to become more familiar with the skill and craft of communicating complex scientific research. This course will provide students with the basic grammatical, stylistic and practical skills required to write effective academic journal articles, theses, or research proposals. In addition, through an innovative partnership with Columbia University Libraries' Digital Science Center, students will learn how to apply these basic skills to their writing through the use of state-of-the-art software and on-line resources. Regular opportunities to write, peer edit and revise throughout the semester will allow students to put what they are learning into immediate practice. It is recommended that undergraduates have taken at least one semester of research for credit before taking this course. Undergraduates should plan to take this course after taking the required Core course University Writing.

CHEM G4232 Introduction to Molecular Modeling. 4.5 points.

Lab Required

Prerequisites: physical chemistry sequence.

Molecular modeling has become an integral part of research in many areas of chemistry, and in industry in drug discovery and materials design. Many experimental papers in the literature are routinely complemented by molecular modeling calculations. Experimental scientists working in industry have a significant advantage if they know how to optimally use modeling software. The course would consist of a normal lecture part plus a lab session every week in which the students learn to use modeling software by working on projects.

CHEM G6169 Materials Chemistry IIB. 2.5 points.

Prerequisites: CHEM C3443 (or equivalent).

This is an introductory course to the field of inorganic nanomaterials chemistry. The course will cover the synthesis, the structural, electronic and magnetic characterization, and the physical properties of zero-, one- and two-dimensional inorganic nanomaterials. Particular emphasis will be devoted to the design of building blocks that can organize into functional assemblies and to the emergence of collective physical properties. The course will also explore the recent and developing electronic and optoelectronic applications of these materials.

CHEM G6231 Intermediate Statistical Mechanics. 2.5 points.

Prerequisites: CHEM G4221 and CHEM G4230.

Phase transitions and critical phenomena; renormalization group methods; classical theory of fluids.

CHEM G6241 Chemical Dynamics. 2.5 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM G4221 or the equivalent.

Theory of the rates and temperature dependence of chemical reactions in gases and liquids.

CHEM G6242 Interfaces and Condensed Phases. 2.5 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM G4221 and CHEM G4230, or their equivalents.

Elements of the physical chemistry and electronic structure of interfaces and solid materials with application to organic conductors and semiconductors.

CHEM G6251 Spectroscopy. 2.5 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM G4221 or the equivalent.

Principles of the interaction of molecules with radiation. Applications of spectroscopy to elucidate molecular structure and bonding.

CHEM G8105 Bioinorganic Chemistry. 2.5 points.

Not offered during 2017-18 academic year.

Coordination chemistry of proteins and nucleic acids and their synthetic analogs.

CHEM G8107 Physical Methods in Inorganic Chemistry. 2.5 points.

Not offered during 2017-18 academic year.

Advanced topics in spectroscopic methods as applied to transition metal complexes.

CHEM G8108 Group Theory. 2.5 points.

Not offered during 2017-18 academic year.

Chemical applications of group theory: structure, bonding and spectroscopy. Ligand field and molecular orbital theories.

CHEM G8110 Applications of Transition-Metal Organometallics to Polymer Chemistry. 2.5 points.

Not offered during 2017-18 academic year.

The use of transition-metal complexes as catalysts for olefin polymerization, and for atom transfer and chain transfer during free-radical polymerizations.

CHEM G8111 Applications of NMR Spectroscopy to Inorganic Chemistry. 2.5 points.

The use of multinuclear NMR spectroscopy in the determination of the structures of inorganic molecules and the use of dynamic NMR spectroscopy (variable temperature NMR and magnetization transfer techniques) to provide information concerned with reaction mechanisms.

CHEM G8120 Polymers in Nanotechnology. 2.5 points.

Polymeric materials have long been ubiquitous items and played important roles in revolutionizing the way we live. Due to the advent of modern polymerization fabrication strategies, polymers are rapidly gaining interest for the development of next generation devices and medical treatment. This course will focus on the chemistry polymers and their use as nanostructured materials created by self-assembly and top-down fabrication techniques. Specifically, the class will be divided into two sections describing the uses of organic nanostructures on a) surfaces and b) as particles. Patterned surfaces will be described in terms of photo-, imprint-, and block copolymer lithography. The preparation of nanoparticles through polymer synthesis, dendrimers, and mechanical manipulation will be the second part.

CHEM G8130 The Chemistry of Nanocrystals. 2.5 points.

This course will provide a discussion of the thermodynamics and kinetics of colloidal crystallization and stabilization, the physical properties of quantum confined semiconductor and metal nanocrystals, methods of nanocrystal characterization, and examples of nanocrystals in technological applications.  Prospective students should be familiar with basic principles of quantum mechanics, thermodynamics of phase transitions, and inorganic chemistry – particularly molecular orbital theory.  Undergraduate students interested in this course should obtain approval from the instructor prior to registering.

CHEM G8149 Synthetic Methods in Organic Chem. II. 4.5 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM G8148.

Construction, analysis, and strategies for the synthesis of complex natural products.

CHEM G8232 Advanced Statistical Mechanics. 2.5 points.

Prerequisites: CHEM G4221 and CHEM G4230, or their equivalents.

Stochastic processes; Brownian motion; Langevin equations and fluctuation-dissipation theorems; reaction rate theory; time correlation functions and linear response theory.

CHEM G8252 Special Topics in Physical Chemistry. 2.5 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM G4221 or the equivalent.

Problems and methods in areas of current research interest.

CHEM G8300 Biophotonics. 2.5 points.

Not offered during 2017-18 academic year.

Biophotonics tools are changing the way many biological problems are addressed by revealing direct and precious visualization information inside live cells, tissues and organisms. This interdisciplinary course will not only provide fundamental knowledge of optics, laser, microscopy, linear and nonlinear molecular spectroscopy, but also introduce physical principles of various emerging microscopy techniques including single-molecule biophysics, multi-photon microscopy, label-free chemical imaging, super-resolution imaging, novel molecular probes, optical coherence tomography and emerging technology. A few guest lectures from expert instructors across the campus are expected.

CHEM G8310 Transition Metals in Organic Synthesis. 2.5 points.

Not offered during 2017-18 academic year.

Recent advances in the development of homogeneous catalysis for selective organic synthesis. Emphasis on both mechanistic and synthetic aspects.

CHEM G8311 Natural Products Chemistry. 2.5 points.

Not offered during 2017-18 academic year.

Topics from recent trends in natural products chemistry, especially in ligand/receptor interactions.

CHEM G8313 Modern Molecular Photochemistry of Organic Compounds. 2.5 points.

Not offered during 2017-18 academic year.

Review of principles of the mechanisms of organic photochemical reactions.

CHEM G8314 Molecular Recognition and Self-Assembly. 2.5 points.

Not offered during 2017-18 academic year.

The chemistry of designing, synthesizing, and studying molecules that self-assemble.

CHEM G8316 Supramolecular Chemistry. 2.5 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM G4147 or the instructor's permission.

Intermolecular interactions are at the structure-reactivity and structure-function relations of many issues in material sciences and biological chemistry. This course will describe the fundamental concepts and methodologies of the field and review its development over the past several decades. Emphasis will be placed on guest-host systems which can be developed based on the paradigm of the chemistry of enzymes.

CHEM G8349 Research Ethics & Philosophy. 2.5 points.

This lecture course aims to address philosophical and ethical questions in scientific research.  What are the most important traits of successful scientists whose discoveries have greatly benefited humanity (and led to Nobel Prizes)?  What distinguishes great science from mediocre or pathological "science"?  What are the ethical standards of scientific research?  How do we identify scientific misconduct or fraud?  Why are ethical standards so critical to the integrity of the research enterprise?  The course requires extensive participation of students in the form of discussions and debates.  Grades will be based on participation, writing assignments, and one oral presentation.

CHEM GR6168 Materials Chemistry IIA. 2.5 points.

Prerequisites: CHEM C3443 (or equivalent).

This is an introductory course to the emerging field macromolecular materials chemistry. The general topics will be based on the chemistry, self-assembly, and performance of block copolymers and conjugated polymers.  Particular emphasis will be devoted to the demands required to drive materials from scientific curiosity to commercialization.  At the fundamental level, the course will cover topics on polymerization techniques, electronic structure of organic semiconductors, characterization strategies, nanostructures and self-assembly.

CHEM GR6222 Quantum Chemistry II. 2.5 points.

Prerequisites: Quantum Chemistry G4221.

Atomic and molecular quantum mechanics: fundamentals of electronic structure, many-body wave functions and operators, Hartree-Fock and density functional theory, the Dirac equation.

Spring 2017: CHEM GR6222
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 6222 001/27566 M W 11:40am - 12:55pm
320 Havemeyer Hall
Richard Friesner 2.5 8/42

CHEM GR8104 Structure Determination in Inorganic Chemistry. 2.5 points.

Not offered during 2017-18 academic year.

The determination of structures by diffraction methods, focusing on single crystal X-ray diffraction, is described. Emphasis is placed on a critical evaluation of published data.

CHEM GR8106 Kinetics. 2.5 points.

Not offered during 2017-18 academic year.

Kinetics and mechanisms of inorganic reactions.

CHEM GU4071 Inorganic Chemistry. 4.5 points.

Prerequisites: CHEM W3443-CHEM W3444 or CHEM W3045-CHEM W3046.

Principles governing the structure and reactivity of inorganic compounds surveyed from experimental and theoretical viewpoints.  Topics include inorganic solids, aqueous and nonaqueous solutions, the chemistry of selected main group elements, transition metal chemistry, metal clusters, metal carbonyls, and organometallic chemistry.

Fall 2017: CHEM GU4071
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4071 001/17834 M W 8:40am - 9:55am
Room TBA
Jonathan Owen 4.5 17/42

CHEM GU4147 Advanced Organic Chemistry. 4.5 points.

Prerequisites: elementary organic and physical chemistry.

The mechanisms of organic reactions, structure of organic molecules, and theories of reactivity. How reactive intermediates are recognized and mechanisms are deduced using kinetics, stereochemistry, isotopes, and physical measurements.

Fall 2017: CHEM GU4147
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4147 001/75049 T Th 10:10am - 11:25am
Room TBA
Dalibor Sames, Jack Norton 4.5 4/42

CHEM GU4148 Synthetic Methods in Organic Chemistry I. 4.5 points.

This course is intended for graduate students and advanced undergraduate students. The main purpose of the course is to introduce students to modern synthetic chemistry via the selected series of topics (synthetic planning and the logic of organic assembly, classical and new reactions/methods and their use in complex target synthesis). Mechanistic underpinning of the discussed reaction processes will also be briefly discussed. For each module (see the content below), specific examples of syntheses of natural products and/or synthetic materials will be provided. In addition to lectures by Prof. Sames, students will select and present relevant papers in the class (the number of student symposia will depend on the final enrollment in this course). The basic knowledge of transition metal chemistry is recommended for the cross-coupling reactions (i.e., structure, electron counting, and elemental reaction types of transition metals).

Fall 2017: CHEM GU4148
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4148 001/17337 M W 10:10am - 11:25am
Room TBA
Tristan Lambert, Tomislav Rovis 4.5 5/42

CHEM GU4221 Quantum Chemistry. 4.5 points.

Prerequisites: elementary physical chemistry.

Basic quantum mechanics: the Schrodinger equation and its interpretation, exact solutions in simple cases, methods or approximation, angular Mementum and electronic spin, and an introduction to atomic and molecular structure.

Fall 2017: CHEM GU4221
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4221 001/24026 M W 11:40am - 12:55pm
Room TBA
Richard Friesner 4.5 3/42

CHEM GU4230 Statistical Mechanics. 4.5 points.

Prerequisites: elementary physical chemistry.
Corequisites: CHEM G4221.

Topics include the classical and quantum statistical mechanics of gases, liquids, and solids.

Fall 2017: CHEM GU4230
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4230 001/63159 M W 1:10pm - 2:25pm
Room TBA
Bruce Berne 4.5 1/42

CHEM U3940 Computational Methods in Chemical Physics. 3 points.

Prerequisites: Basic physics, including Newton's laws of motion \nPrior experience with computer programming; C, C++, Java and/or Python are preferred. Some experience with differential equations, probability, and statistics is preferred but not required

Martin Karplus, Michael Levitt, and Arieh Warshel won the 2013 Nobel Prize in Chemistry for laying the foundations for today's computer models that combine principles of classical (Newtonian) physics and quantum physics to better model the fine details of chemical processes.  In this course, you will learn the basics of these computational simulation methods, which are used to solve problems in biology, chemistry and physics.  Additionally, the course will introduce a chemistry - and physics - motivated perspective on computer science algorithms used to approximately solve classic NP-hard problems.  Topics will include several important and widely developed simulation methods in physical chemistry, including molecular dynamics, Monte Carlo, and simulated annealing.  You will write your own code to simulate a liquid of interacting Lennard-Jones particles, model a carbon nanotube in aqueos solution, and approximate solutions to the traveling salesman problem.

CHEM W2494 Organic Chemistry Laboratory II (Synthesis). 1.5 point.

Lab Fee: $62.00

Prerequisites: CHEM W1403-CHEM W1404; CHEM W1500; CHEM W2493.
Corequisites: CHEM W2444.

Please note that you must complete CHEM W2493 before you register for CHEM W2494. This lab introduces students to experimental design and trains students in the execution and evaluation of scientific data. The technique experiments in the first half of the course (CHEM W2493) teach students to develop and master the required experimental skills to perform the challenging synthesis experiments in the second semester. The learning outcomes for this lab are the knowledge and experimental skills associated with the most important synthetic routes widely used in industrial and research environments. Attendance at the first lab lecture and laboratory session is mandatory. Please note that CHEM W2494 is the second part of a full year organic chemistry laboratory course. Students must register for the lab lecture section (CHEM W2496) which corresponds to their lab section. Students must attend ONE lab lecture and ONE lab section every other week. Please contact your advisors for further information.

CHEM W2507 Intensive General Chemistry Laboratory. 3 points.

CC/GS: Partial Fulfillment of Science Requirement
Lab Fee: $140.

Prerequisites: CHEM W1604 or CHEM W3045.

As of academic year 2016-17, this course is now CHEM UN1507. A student-centered experimental course intended for students who are taking or have completed CHEM W1604 (Second Semester General Chemistry Intensive Lecture offered in Fall), CHEM W3045 (Intensive Organic Chemistry offered in Fall), or CHEM W3046 (Intensive Organic Chemistry Lecture offered in Spring). The course will provide an introduction to theory and practice of modern experimental chemistry in a contextual, student-centered collaborative learning environment. This course differs from CHEM W1500 in its pedagogy and its emphasis on instrumentation and methods. Students must also attend the compulsory Mentoring Session. Please check the Directory of Classes for details. Please note that CHEM W2507 is offered in the fall and spring semesters.

CHEM W3045 Intensive Organic Chemistry I (Lecture). 3.5 points.

CC/GS: Partial Fulfillment of Science Requirement, Recitation Section Required

Prerequisites: a grade of 5 on the Chemistry Advanced Placement exam and an acceptable grade on the Department placement exam or an acceptable grade in CHEM W1604.

As of academic year 2016-17, this course is now CHEM UN2045. Premedical students may take CHEM W3045CHEM W3046CHEM W2507 and CHEM W3545 to meet the minimum requirements for admission to medical school. This course covers the same material as CHEM W3443 - CHEM  W3444, but is intended for students who have learned the principles of general chemistry in high school OR have completed CHEM W1604 in their first year at Columbia. First year students enrolled in CHEM W3045-CHEM W3046 are expected to enroll concurrently in CHEM W2507. Although CHEM W3045 and CHEM W3046 are separate courses, students are expected to take both terms sequentially. A recitation section is required. Please check the Directory of Classes for details and also speak with the TA for the course.

CHEM W3046 Intensive Organic Chemistry II (Lecture). 3.5 points.

Prerequisites: CHEM W3045

As of academic year 2016-17, this course is now CHEM UN3046. Premedical students may take CHEM W3045CHEM W3046, and CHEM W3545 to meet the minimum requirements for admission to medical school. This course covers the same material as CHEM W3443-CHEM  W3444, but is intended for students who have learned the principles of general chemistry in high school OR have completed CHEM W1604 in their first year at Columbia. First year students enrolled in CHEM W3045-CHEM W3046 are expected to enroll concurrently in CHEM W2507. Although CHEM W3045 and CHEM W3046 are separate courses, students are expected to take both terms sequentially. A recitation section is required.  Please check the Directory of Classes for details and also speak with the TA for the course.

CHEM W3443 Organic Chemistry I (Lecture). 3.5 points.

Recitation Section Required

Prerequisites: CHEM W1404 or CHEM W1604 and CHEM W1500

As of academic year 2016-17, this course is now CHEM UN2443. The principles of organic chemistry. The structure and reactivity of organic molecules are examined from the standpoint of modern theories of chemistry. Topics include stereochemistry, reactions of organic molecules, mechanisms of organic reactions, syntheses and degradations of organic molecules, and spectroscopic techniques of structure determination. Although CHEM W3443 and CHEM W3444 are separate courses, students are expected to take both terms sequentially.  Students must ensure they register for the recitation which corresponds to the lecture section. Please check the Directory of Classes for details.

CHEM W3444 Organic Chemistry II (Lecture). 3.5 points.

CC/GS: Partial Fulfillment of Science Requirement, Recitation Section Required

Prerequisites: CHEM W1404 or CHEM W1604 and CHEM W1500.

As of academic year 2016-17, this course is now CHEM UN2444. The principles of organic chemistry. The structure and reactivity of organic molecules are examined from the standpoint of modern theories of chemistry. Topics include stereochemistry, reactions of organic molecules, mechanisms of organic reactions, syntheses and degradations of organic molecules, and spectroscopic techniques of structure determination. Although CHEM W3443 and CHEM W3444 are separate courses, students are expected to take both terms sequentially.  Students must ensure they register for the recitation which corresponds to the lecture section. Please check the Directory of Classes for details.

CHEM W3493 Organic Chemistry Laboratory I (Techniques). 1.5 point.

Lab Fee: $63.00

Prerequisites: CHEM W1403-CHEM W1404; CHEM W1500
Corequisites: CHEM W3443.

As of academic year 2016-17, this course is now CHEM UN2493. Techniques of experimental organic chemistry, with emphasis on understanding fundamental principles underlying the experiments in methodology of solving laboratory problems involving organic molecules.  Attendance at the first lab lecture and laboratory session is mandatory. Please note that CHEM W3493 is the first part of a full year organic chemistry laboratory course.  Students must register for the lab lecture section (CHEM W3495) which corresponds to their lab section. Students must attend ONE lab lecture and ONE lab section every other week.  Please contact your advisors for further information.

CHEM W3494 Organic Chemistry Laboratory II (Synthesis). 1.5 point.

Lab Fee: $62.00

Prerequisites: CHEM W1403-CHEM W1404; CHEM W1500; CHEM W3493.
Corequisites: CHEM W3444.

As of academic year 2016-17, this course is now CHEM UN2494. Please note that you must complete CHEM W3493 before you register for CHEM W3494. This lab introduces students to experimental design and trains students in the execution and evaluation of scientific data. The technique experiments in the first half of the course (CHEM W3493) teach students to develop and master the required experimental skills to perform the challenging synthesis experiments in the second semester. The learning outcomes for this lab are the knowledge and experimental skills associated with the most important synthetic routes widely used in industrial and research environments. Attendance at the first lab lecture and laboratory session is mandatory. Please note that CHEM W3494 is the second part of a full year organic chemistry laboratory course. Students must register for the lab lecture section (CHEM W3496) which corresponds to their lab section. Students must attend ONE lab lecture and ONE lab section every other week. Please contact your advisors for further information.

CHEM W3545 Intensive Organic Chemistry Laboratory. 3 points.

Lab Fee: $125.

Prerequisites: CHEM W3045 and CHEM W3046 and CHEM W2507.

As of academic year 2016-17, this course is now CHEM UN2545. The course covers the same material as CHEM W3493-CHEM W3494, but is intended for those students who have taken Intensive Organic Chemistry, CHEM W3045-CHEM W3046, and for students who intend to major in Chemistry, Biochemistry, Chemical Physics, or Environmental Chemistry.

The University reserves the right to withdraw or modify the courses of instruction or to change the instructors as may become necessary.